How to Use Paracetamol Correctly?

The liver is a large organ in the abdomen that performs many important bodily functions, including blood filtering.⁶

The liver is an essential organ, performing hundreds of functions necessary to sustain life.⁶

Liver is the major organ responsible for paracetamol metabolism (Conjugation with glucouronic acid approximately 55%, and sulphuric acid 35%).²

The pharmacologically inactive metabolites are excreted via kidneys (only 4% are excreted unaltered).²

If you take too much paracetamol, your liver can't handle it.

This can lead to a buildup of harmful substances, which is dangerous. This is called 'liver toxicity'.

That's why it's important to always take the right amount of paracetamol and to ask your doctor if you have any questions. It's also important to tell your doctor about any other medications you're taking..

Can I give paracetamol to a child?

No, Doliprane is for oral administration in adults aged 18 and above.²

The usual dosage is:²

• The usual dosage for Doliprane is 1 tablet, 2 to 4 times a day.
• Administration can be repeated at 4 - 8 hour intervals, depending on the clinical situation.
• Maximum daily dose is 4 tablets (i.e., 4 g paracetamol/day).

Paracetamol should only be used during pregnancy after a careful risk-benefit assessment.
If clinically needed, paracetamol can be used during pregnancy however it should be used at the lowest eff­ective dose for the shortest possible time and at the lowest possible frequency.²

If you're breastfeeding, it's best to follow your doctor's advice on the correct dosage of paracetamol.²

Doliprane is contraindicated in the following situations:²

• Hypersensitivity to the active substance or to any of the excipients.
• Serious hepatic disease.
   

If you have any of the following conditions, talk to your doctor before taking paracetamol:²

• In therapeutic doses paracetamol is relatively nontoxic. However, allergic reactions may occur, including anaphylaxis.
• In the following situations the medicinal product should only be used with particular caution (i.e., with adjustment of doses or intervals of administration) and under medical supervision:
  • Hepatic insufficiency (e.g., due to chronic alcohol abuse, hepatitis)
  • Renal insufficiency.
  • Gilbert's disease
• Precaution in the administration of paracetamol is recommended for patients with severe renal impairment, severe liver disease or severe hemolytic anemia.
• Paracetamol must be used with caution in situation dehydration or malnutrition.
• Prolonged use of analgesics or inappropriate use of high doses can cause headaches which should not be treated with increased doses of the medicine.
• The medicine should not be used for more than 10 days in adults unless prescribed by the doctor.
• In situations of high fever (above 39°C), lasting more than 3 days or recurrent fever, paracetamol should not be used unless prescribed by the doctor, as these situations may indicate a serious illness requiring medical assessment and treatment.
• During treatment with Doliprane, do not take other medicines containing paracetamol.

Paracetamol is generally safe and effective when used correctly.²

This means taking the right dose for the right person and at the right time.

"I make sure to follow the instructions and take the correct amount of medication each time."

Overdosing can seriously harm my liver. If my symptoms don't go away, I'll see a doctor.